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TGF-beta as a target for novel analgesics

Researchers in the Pasricha laboratory at Stanford have shown that antagonists to transforming growth factor-β (TGF-β) could be used to treat pain because TGF-β plays a direct role in sensitizing nociceptors (pain-sensing neurons). TGF-&be...
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A photocrosslinkable peptide-MHC reagent for detecting and purifying antigen-specific T cells

Researchers at Stanford have developed a new method for detecting and purifying antigen-specific T cells by attaching a crosslinker to the MHC bound peptide or to the MHC itself. A photocrosslinker is introduced to a site just outside the core TCR-recogni...
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