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Fluorescent labels with tunable properties - New Fluorescent Deoxyribosides and their Incorporation into Combinatorial Fluorophore Arrays

This invention consists of combinatorial arrays of fluorophores (CFAs) built on a repeating oligomeric (e.g.,DNA) backbone. With the DNA backbone, the invention starts with a number of synthesized new fluorescent monomer molecules in which the fluorescent...
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Cell-based assay for Wnt signaling

Cells that stably express a luciferase reporter construct, driven by the TCF transcription factor have been made. These cells respond to added Wnt protein in a highly reproducible and quantifiable way and are very suitable to test for the activity of cand...
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