Docket #: S98-122
Soluble CD81 Fusion Constructs
Soluble CD81 molecules were constructed for the purpose of identifying a postulated ligand to CD81. Recently CD81 has been claimed by others to be a candidate for a receptor for the human hepatitis C virus (HCV). The soluble CD81 could be used to block binding of viral proteins to cells.
Advantages
- Such soluble constructs have not been made previously.
Publications
- Proc. Natl. Acad. Sci 95: 2458 (March 1998)
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