Anti-Set1p monoclonal antibody

Researchers in the laboratory of Dr. Michael Cleary at Stanford University have developed anti-Set1p monoclonal antibodies to study chromatin regulation and histone methylation. Histone methylation has emerged as a modification for recruitment of proteins that determine transcriptional accessibility of genes. Set1p is a yeast protein that is a component of a seven-member complex that is required for a specific histone methylation. The anti-Set1p antibodies could be used to study chromatin remodeling as well as epigenetic regulation of developmental and sex-specific gene expression.