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Docket #: S08-436

Magnetic Separation for Cell Sorting and Analysis

Engineers in Prof. Shan Wang's laboratory have developed a patented magnetic sifter device for high throughput cell sorting. This technology employs magnetic nanobead probes to tag cells of interest from raw samples. Those tags are used to sift the molecules through pores specifically configured for biological cell purification. This invention has ultra-high capture and release efficiencies and can easily interface with standard flow equipment with applications in a variety of downstream cellular analyses.

Applications

  • Cell sorting for:
    • biological research
    • diagnostics
    • biowarfare detection
    • genomics and proteomics
    • collection and isolation of rare cells

Advantages

  • High throughput - greater than 1 ml/hr
  • Ultra-high capture and release efficiencies - greater than 95%
  • Multi-functional probes - the same probes can potentially be used for both capture and detection
  • Low cost, easy to use, simple design

Publications

Patents

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