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Microfluidics tools for automated surveillance of insect-borne bioagent


Stanford Reference:

12-314


Abstract


Researchers in Prof. Manu Prakash’s laboratory have developed a microfluidics platform for large-scale automated collection of insect saliva and downstream quantification and detection of insect vector-borne diseases such as malaria, West Nile virus or Dengue fever. This device enables coverage of large surveillance areas because the insect analysis is performed without the tedious, time-consuming, expert-level examination that is currently required. This surveillance platform has integrated downstream processing to carry out multiplex testing for individual microbe, parasite, or species identification with applications in disease monitoring, agricultural pest control, or biodiversity mapping research.

Stage of Research
The inventors have demonstrated proof of principle by performing species-level identification from mosquito saliva using PCR.

Applications


  • Public health/infectious disease monitoring - tracking insect vector-borne diseases that infect humans (e.g. malaria, West Nile virus, Dengue fever) and quantifying biocontrol
  • Agriculture - monitoring insect-borne diseases that affect crops and other plants
  • Research - field data collection for identification of species and ecological sampling

Advantages


  • Automated sample collection, detection and quantification - does not require tedious, time consuming, expert-level analysis or manual manipulation of individual insects
  • Scalable and low cost platform - can monitor large surveillance areas and low parasite count across a diverse range of insects
  • Multiplex analysis - integrated downstream processing to identify individual pathogens, microbes and species in field conditions

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Innovators & Portfolio



Date Released

 10/2/2012
 

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Related Keywords


genetic assays   monitoring instrumentation   biosurveillance   dengue fever   virus   viral   research tool   diagnostic   MEMS: microfluidics   west nile virus   public health   Pathogen Detection   microfluidics   microfluidic device   malaria   infectious disease   
 

   

  

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S12-314 Microfluidics tools for automated surveillance of insect-borne bioagent