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A Novel Blood Test for the Diagnosis of Celiac Disease


Stanford Reference:

12-342


Abstract


Researchers in Dr. Mark M. Davis' lab have developed a blood test to diagnose celiac disease (CD) which requires gluten ingestion for only 1-3 days. CD is a common incurable autoimmune disease precipitated by gluten ingestion and characterized by small intestine mucosal injury and nutrient malabsorption. Many people eliminate gluten from their diets without an established diagnosis of CD. Currently available tests for CD, including antibody tests and intestinal biopsy, are inaccurate in patients on a gluten-free diet and require prolonged gluten exposure. This is often intolerable to patients and thus prevents an accurate diagnosis. This technology overcomes this limitation as it allows diagnosis of CD in people already on a gluten-free diet after voluntary gluten ingestion for a short period of time.

Stage of Research
Initial clinical validation studies have been conducted and show promise for reliable clinical diagnosis of CD with only short-term gluten exposure.

Applications


  • Clinical diagnostic test for CD

Advantages


  • Non-invasive
  • Inexpensive - less costly than endoscopy
  • Short 1-3 day period of gluten exposure instead of 4 or more weeks
  • Diagnostic for people already on a gluten-free diet

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Date Released

 7/23/2013
 

Licensing Contact


Ximena Ares, Licensing Associate
650-724-0960 (Direct)
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Related Keywords


diagnostic: antibody   diagnostic: assay   diagnostic: autoimmunity   diagnostic: immunoassay   celiac   celiac disease   diagnostic clinical   medical diagnostics   diagnostic: blood   diagnostic: detection   diagnostic: inflammation   non-invasive diagnostic test   
 

   

  

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