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ROR2 (Nt 2535-2835) mouse monoclonal antibody


Stanford Reference:

11-215B


Abstract


Researchers in Dr. Roeland Nusse’s lab have developed a mouse monoclonal antibody to ROR2 (Nt 2535-2835). ROR2 is a membrane bound receptor tyrosine kinase that is activated by non-canonical Wnt signaling through its association with Wnt5. Mutations in ROR2 can cause disease and ROR2 has been shown to have pro-tumorigenic effects for a variety of tumor types. This mouse monoclonal antibody is an IgG1 isotype and can be used to detect mouse and human ROR2 protein expression by immunoblotting and immunohistochemistry (IHC).

Applications


  • IHC — detects ROR2 protein in paraffin-embed tissues
  • Immunoblotting

Advantages


  • Specific for Ror2 — does not detect the Ror1 homolog

Publications



Examples of IHC staining with this Ror2 antibody


Staining on a leiomyosarcoma tumor

Staining on a lung cancer

Staining on two breast cancers


Related Web Links



Innovators & Portfolio



Date Released

 3/5/2014
 

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Related Keywords


research tool: antibody   monoclonal antibodies   research tool: reagent   
 

   

  

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78-017 Monoclonal Antibodies: 11-6 anti-Ig-5b, 11-5 anti-I-A (2), 11-4 anti-H-2Kk, 11-3 anti-I-A917), 10-4 anti-Ig-5a, H-12 anti-THY 1.2
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S11-215B ROR2 (Nt 2535-2835) mouse monoclonal antibody