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Monoclonal Antibody for Hypocretin-1 (MAb 310)


Stanford Reference:

91-095


Abstract


Researchers in Prof. Emmanuel Mignot’s laboratory developed a mouse monoclonal antibody to the N-terminal end of the hypocretin-1 protein (Hcrt-1, also known as orexin-A). Hcrt-1 is an excitatory neuropeptide hormone with established effects on wakefulness, mood and lipid metabolism. The absence of hcrt-1 can cause narcolepsy. This antibody has applications for narcolepsy diagnostics and for basic research of sleep disorders and metabolism.

Applications


  • Diagnostic tool to provide accurate early diagnosis for human or animal narcolepsy
  • Research tool to study lipid metabolism and sleep disorders

Publications



Related Web Links



Innovators & Portfolio


  • Emmanuel Mignot   
  • Shahrad Taheri   

Date Released

 9/9/2013
 

Licensing Contact


Andrea Pesce, Licensing Liaison
(650) 725-8062 (Business)
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[-] Map/Timeline

78-017 Monoclonal Antibodies: 11-6 anti-Ig-5b, 11-5 anti-I-A (2), 11-4 anti-H-2Kk, 11-3 anti-I-A917), 10-4 anti-Ig-5a, H-12 anti-THY 1.2
79-066 Mouse Anti-Human Hybridomas L243, L17F15
82-008 A Monoclonal Antibody Specific For Mouse Granulocytes

more technologies

Related Keywords


monoclonal antibodies   narcolepsy   research tool: antibody   diagnostic: antibody   orexin   diagnostic: assay   
 

   

  

Also of Interest...
78-017 Monoclonal Antibodies: 11-6 anti-Ig-5b, 11-5 anti-I-A (2), 11-4 anti-H-2Kk, 11-3 anti-I-A917), 10-4 anti-Ig-5a, H-12 anti-THY 1.2
79-066 Mouse Anti-Human Hybridomas L243, L17F15
82-008 A Monoclonal Antibody Specific For Mouse Granulocytes

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S91-095 Monoclonal Antibody for Hypocretin-1 (MAb 310)