Engineers in Prof. Zhenan Bao's lab have developed highly conductive, stretchable composite hydrogel materials that can be used as soft electrodes that match the mechanical properties of a range of biological tissues.
Researchers at Stanford and their colleagues have developed easily expressed Wnt agonist and antagonists. Wnts are central mediators of development as they influence cell proliferation, differentiation and migration.
Researchers in Prof. Brian Feldman's laboratory have developed a patented drug screen to identify compounds that could potentially treat obesity and metabolic disease by converting cells to calorie-burning brown fat.
Summary: Stanford researchers at the Melosh Lab have proposed a non-invasive, high electrode density, high resolution (100 micrometers to 10 nanometers) neural device implantation for electrical stimulation of neural/biological tissues.
Stanford researchers have developed an injectable, biocompatible hydrogel consisting of extracellular matrix (ECM) from human cadaveric tendons as a potential scaffold for guided tissue regeneration and tissue engineering purposes.
Researchers in Prof. Irving Weissman's laboratory have developed cell culture techniques to rapidly and efficiently derive pure populations of mesodermal cells from human pluripotent stem cells (hPSCs).
Researchers at Stanford have engineered proteins to selectively sensitize T cells to IL-2. The ability to manipulate immune cells for therapeutic use is of great clinical interest. Cytokines are signaling molecules that can be used to alter cellular behavior.
Researchers at Stanford have developed methods using click chemistry to immobilize and concentrate therapeutic factors on a tissue to improve wound healing.
Researchers at Stanford have developed methods to enhance bone healing in diabetic patients, who often suffer from impaired fracture healing due to a deficiency in hedgehog signaling in their skeletal stem cells.
Researchers at Stanford have developed methods to classify and treat MYC-driven hematopoietic cancers. The MYC oncogene drives the proliferation and survival of many hematopoietic cancers. These cancers are highly aggressive and do not respond to conventional chemotherapies.
Researchers in Dr. Anton Wyss-Coray's lab have identified a new therapeutic avenue for treatment of age-related neurodegenerative diseases. Cerebrovascular changes and inflammation are key features of brain aging and neurodegeneration.
Researchers in Prof. Irving Weissman's lab have developed and patented antibodies and methods to prevent the formation of teratomas from human pluripotent stem cells used for regenerative medicine, cell therapy or research.
Researchers in Prof. Hemamala Karunadasa's laboratory have developed inexpensive, robust, high capacity hybrid materials for reversible or irreversible capture of halogens (chlorine, bromine, and iodine gas).
Researchers at Stanford have developed methods to identify, isolate, and use specific progenitor cell populations to generate adipose tissue and functional blood vessels in vivo.