Docket #: S23-254
Novel Therapeutic Target for Antibody-based Autoimmune Conditions
Researchers at Stanford have discovered a novel therapeutic strategy to treat antibody -mediated autoimmune anemia and thrombocytopenia.
Patient-derived immunoglobulin (IVIG) stands as the gold standard treatment for numerous autoimmune conditions, such as antibody-mediated anemias and thrombocytopenias. However, the treatment is both expensive and has limited availability, highlighting an unmet need to find more accessible therapies.
Now, Stanford researchers have found a novel approach that could solve this issue. In this approach, antibodies against red blood cell expressed antigens could be administered without the need for IVIG and it has been shown to be effective in animal models.
Stage of Development
Research - In vivo
Applications
- Therapeutic for treating autoimmune conditions impacting RBC
- Therapeutic for treating autoimmune conditions impacting platelets
Advantages
- Novel target for treating antibody-mediated autoimmune conditions (e.g. thrombocytopenias)
- Cheaper than existing therapeutic strategies to treat autoimmune diseases affecting red blood cells and platelets
- More accessible therapeutic for antibody-mediated autoimmune conditions
Related Links
Similar Technologies
-
Blocking and Reversing Extracellular Vesicle-Driven Transcriptomic Transformation with Annexin V Treatment S21-223Blocking and Reversing Extracellular Vesicle-Driven Transcriptomic Transformation with Annexin V Treatment
-
Therapeutic target for treating age-related neurodegenerative diseases S15-403Therapeutic target for treating age-related neurodegenerative diseases
-
Blocking an immune receptor signal to treat obesity and fatty liver disease S23-015Blocking an immune receptor signal to treat obesity and fatty liver disease