Stanford researchers in the laboratory of Dr. Daria Mochly-Rosen have developed novel small molecules for modulating ALDH2 (mitochondrial aldehyde dehydrogenase-2).
Researchers at Stanford have developed prodrug derivatives of protein kinase C (PKC) modulators that have lower toxicity and are more effective than the parent compound. PKC modulators are being developed to treat a variety of diseases.
Researchers in Prof. A.C. Matin's laboratory have developed a versatile exosome (extracellular vesicle, "EV") drug delivery platform that can selectively target therapeutic agents to tumors or other tissues that overexpress extracellular receptors.
Stanford researchers have developed a new class of materials that enable new strategies for the efficient delivery of messenger RNA (mRNA) into cells and animals. The delivery materials are easily prepared (2 steps), stable and readily tuned.
Stanford researchers have developed a gene therapy that combines a retinal ganglion cell (RGC)- specific promoter with CRISPR gene editing to provide effective neuroprotection in optic neuropathies.
Researchers at Stanford have developed a targeted delivery system using carbon nanotubes to specifically deliver cardiovascular drugs to treat atherosclerosis. A feature of atherosclerotic plaque is the accumulation of apoptotic cells.
Current injectable hydrogel materials have fast erosion and limited tunability of their mechanical properties at different stages of applications, limiting their biomedical applications.
Researchers at Stanford have developed a new therapeutic to promote survival of retinal ganglion cells (RGCs) and optic nerve regeneration after traumatic injury or optic neuropathies.
A team of Stanford researchers has developed a precisely controlled hydrogel drug delivery system that prevents scarring and promotes wound healing in large, full thickness wounds.
Stanford researchers have patented a hydrogel system which allows for the easy encapsulation of cells and biomolecules without requiring external changes in environmental conditions or exposure to chemical crosslinkers.
A team of researchers at Stanford and the University of Connecticut have developed a method to deliver contrast agents through a patient-friendly sublingual or buccal film that provides prolonged continuous release for ongoing optical imaging.
Stanford researchers have demonstrated a new passive cavitation mapping algorithm based on sound localization of multiple scatters of cavitation. It shows improved resolution as compared to existing passive cavitation mapping algorithms based on a basic beamforming.
Stanford researchers at the Airan Lab have developed a new method for robust and spatiotemporally precise non-invasive neuromodulation that could transform both basic and clinical neuroscience.
Researchers at Stanford have developed methods to overcome the limited packaging capacity of adeno-associated virus (AAV) vectors and enable their use in integration of large transgenes.