Stanford researchers have engineered retroviral and virus-like delivery systems for producing universal pseudotyped vehicles for cell and gene therapies.
Skin wounds invariably heal by developing fibrotic scar tissue, which can result in devastating disfigurement, growth restriction and permanent functional loss.
Stanford researchers have developed technology enabling pooling and simultaneous testing of engineered T cells from multiple human donors. This invention increases scale and reduces costs for diagnostic, and pre-clinical development of engineered T cell therapies.
Stanford scientists have developed a strategy that enables simultaneous and combinatorial genetic screening across different types of genetic perturbations (gene knockouts, knock-ins, overexpression, and gene domain modification).
Stanford researchers have developed a strategy for engineering next-generation cell therapies where gene knock-in is tightly coupled to gene knockout, preventing dangerous side effects associated with cells that have the knockout in the absence of the knock-in and vice versa.
Researchers at Stanford University have developed a method and composition of immunomodulatory compounds that prevent and reverse T cell exhaustion, improving on existing CAR T cell therapies.
A team of Stanford researchers has identified a group of small molecules that can prevent or reverse T cell exhaustion, thereby increasing the effectiveness of adoptive T cell therapies to fight cancer or chronic infections.
Stanford researchers have identified that increased oxidative stress is a key molecular signature of fatigue-based conditions including Long COVID and myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS).
Liquid biopsies have emerged as a groundbreaking approach in cancer diagnostics, enabling the detection of DNA shed by cancer cells through a simple blood test. However, cancer cells also shed RNA into the blood.
Stanford researchers have developed a next-generation protein sequencing platform capable of identifying all the proteins in a cell at single amino acid resolution.
Stanford scientists develop a method for assessing patient risk of developing postsurgical neurocognitive complications using a combination of biomarkers. This method will ensure improved interventions and treatment outcomes.
Stanford inventors have developed a method of using human induced pluripotent stem (hiPS) cells to generate three-dimensional neural floorplate organizers that are functionally active and capable of choreographing midline brain development.
Stanford scientists have developed an innovative microfracture surgery method that significantly enhances cartilage repair. By combining this surgery technique with targeted delivery of specific growth factors (e.g.
Researchers in the Herzenberg laboratory at Stanford University have patented a method to quantify antigens during flow cytometry without the use of calibrators.