Cell culture is a central technique used for a plethora of research applications including in the modeling of complex diseases, creating transgenic animals, gene therapy, cell therapy, regenerating lost tissue, and organ biogenesis.
Stanford scientists have developed an accurate, rapid, and efficient tool for in vivo microglial manipulation to validate gene functions after transcriptomic analysis.
Cancer specific antigenic epitopes called neoantigens are necessary for effective adoptive T cell therapies. Neoantigens generate cytotoxic T lymphocytes (CTLs) and CTLs can be exploited to safely target and eliminate cancerous cells.
Researchers in the Nakauchi lab at Stanford University have shown that the contribution of human donor cells to tissues and organs can be increased in an interspecies host embryo by knocking out insulin growth factor 1 receptor (Igf1r).
Researchers at Stanford have developed chemically defined, polyvinyl alcohol (PVA)-based media for culturing hematopoietic stem cells and immune cells (e.g., T cells).