This antibody is directed against the human LMO2 antigen, which is expressed as a transcription factor in certain lymphomas and leukemias. We have recently shown that it identifies those lymphomas derived from germinal center B cells.
The 4G7 hybridoma secretes an IgG1 antibody that is specific for normal and malignant B lymphocytes and can be used for the study of B cell differentiation and for the characterization of lymphoid malignancies.
12E7 antibody that can be used to diagnose and differentiation of peripheral ectodermal tumors (PNET) and Ewing's sarcomas, as well as in therapeutic applications and bone marrow transplantation.