Researchers in Prof. W.E. Moerner's laboratory have developed a compact point spread function (PSF) that enables optical imaging in three dimensions with nanoscale precision using a limited number of photons.
W.E. Moerner and Adam Cohen have patented the Anti-Brownian ELectrokinetic trap (ABEL trap) which can trap, measure, and manipulate sub-micron objects (e.g. single molecules) in solution at ambient temperature.