S21-290 MANIfold: Systematic characterization of nucleic acid thermodynamics via high-throughput fluorescence melt experiments MANIfold is a novel method developed for systematic, high throughput measurements of nucleic acid secondary structure. William Greenleaf Rhiju Das Hannah Wayment-Steele Eesha Sharma Anthony Ho Winston Becker Yuxi Ke
S18-318 TUNABLE RNA INTERFERENCE VIA NUCLEOTIDE MISMATCH DESIGN Researchers at Stanford, the University of Massachusetts and the Chan Zuckerberg Biohub have developed methods to increase or decrease RNA interference target cleavage rates. William Greenleaf Benjamin Ober-Reynolds Winston Becker Phillip Zamore Karina Jouravleva Samson Jolly