Inventors at Stanford developed a method to leverage mass cytometry, a type of flow cytometry utilizing mass spectrometry, for the detection of heavy metals in leukocytes from individuals exposed to heavy metals in elevated air pollution.
Researchers in Dr. Holden Maecker's lab have developed platinum-labeled probes to expand the analytical capacity of mass cytometry instruments. Currently, analytical capacity is limited by the ability to label specific probes with appropriate metal ions.
Researchers at Stanford have developed methods and reagents to improve and expand the capabilities of tyramide signal amplification (TSA) for simultaneous detection of low abundance biomolecules.
Researchers in Prof. Sylvia Plevritis' laboratory have developed an algorithm designed to optimize cancer combination therapy for individual patients by analyzing distinct single-cell responses from heterogeneous tumors.
Stanford researchers have developed a statistical algorithm termed Single Cell Linkage Using Distance Elimination (SLIDE) to analyze large-scale data sets without reducing their dimensionality, including those generated by single-cell mass cytometry.
GateFinder is a flexible, automated, objective algorithm that quickly analyzes complex mass cytometry datasets to identify simple signatures (“gates”) for FACS (fluorescent automated cell sorting) purification.