Stanford scientists have developed a working model that chemotherapy drugs induce peripheral neuropathy by activating a pathway that favors neuronal degeneration and impairs sensory neuron function.
Stanford researchers have developed a method for targeted focused ultrasound application to peripheral nerves to suppress acute pain. This invention can non-invasively concentrate ultrasound waves onto peripheral nerves without impacting surrounding tissue.
Stanford researchers in the laboratory of Dr. Daria Mochly-Rosen have developed novel small molecules for modulating ALDH2 (mitochondrial aldehyde dehydrogenase-2).
Researchers at Stanford have discovered new, chemically distinct opioid receptor ligands that may be used to develop safer opioid therapeutics. Opioids are ligands that bind to the mu, delta, and/or kappa opioid receptors.
Stanford researchers at the Sattely Lab have discovered six podophyllotoxin biosynthetic genes and their polypeptide products from the plant, Podophyllum hexandrum (mayapple).