Researchers at Stanford have developed a probe, NIRDye812, which improves contrast between healthy and diseased tissues for fluorescence-guided cancer surgery applications.
Researchers in the Appel lab have developed hydrogels for tumor inoculation that improve precision and statistical power in preclinical mouse models of cancer.
Tracking in vivo cell distribution, migration, and engraftment using conventional techniques including MRI, PET/CT and conventional optical imaging is often hindered by low resolution, radioactive risks, and limited tissue penetration depth.
Temporally precise, noninvasive control of neural circuitry is a long-sought goal of neuroscientists and biomedical engineers. Stanford University researchers in the laboratory of Dr.
Researchers in the laboratories of Dr. Karl Deisseroth and Dr. Peter Hegemann have engineered mutant ChR2 (Channelrhodopsin-2) proteins with light-sensitivity that is increased by orders of magnitude compared to wild-type ChR2.
Researchers in Prof. Karl Deisseroth's lab have discovered and engineered new microbial opsin proteins and cell trafficking tools to enable selective cell-type specific, light-sensitive switches for neuromodulation.
Researchers in Dr. Karl Deisseroth's lab have developed a selective approach to treat anxiety. Anxiety is characterized by several features that are coordinately regulated by diverse neuronal system outputs.
Researchers in Dr. Jianghong Rao's lab have developed nanoprobes for monitoring drug-induced hepatotoxicity in vivo in real time. Drug toxicity is a long-standing concern of modern medicine.
A team of Stanford researchers has developed a highly sensitive, single molecule in situ hybridization system called Proximity Ligation- in situ hybridization (PLISH), which merges the specificity of proximity ligation, the sensitivity of probe tiling, and the high signal inte
Researchers in Dr. Karl Deisseroth's lab have engineered a channelrhodopsin variant that can be stimulated by red light and has fast stimulation frequencies. In neurons, channelrhodopsins are light activated protein channels that induce action potential firing.
Researchers in Dr. Michael Lin's lab have developed a fluorescent voltage sensor for non-invasive optical monitoring of electrical events in living cells in vitro and in vivo.
Stanford and Rockefeller researchers have identified and developed dynein-specific inhibitors that have significant medical applications involving mitotic spindle assembly, organelle transport, and primary cilia formation.
RNKp30 monoclonal antibodies were generated by immunizing BALB/c mice with rNKp30-Fc fusion protein. The rNKp30-Fc fusion protein is a soluble protein consisting of the extracellular domain of rNKp30 fused to the Fc domain of human IgG1.