Cancer specific antigenic epitopes called neoantigens are necessary for effective adoptive T cell therapies. Neoantigens generate cytotoxic T lymphocytes (CTLs) and CTLs can be exploited to safely target and eliminate cancerous cells.
Researchers at Stanford have developed chemically defined, polyvinyl alcohol (PVA)-based media for culturing hematopoietic stem cells and immune cells (e.g., T cells).