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1D6 mab reacting with human CD81


Stanford Reference:

98-059


Abstract


1D6 is a monoclonal antibody (mAb) which recognizes human CD81. It was identified by its ability to induce aggregation of a human lymphoma B cell line. This mAb is capable of inducing an antiproliferative effect in B cells

Applications


  • Flow cytometric studies
  • Immunoprecipitation
  • Western blots
  • Immunohistochemistry (in paraffin embedded tissue sections)

Advantages


  • Most potent inducer of biological responses (i.e. antiproliferative effect, induction of homotypic adhesion, and inhibition of motility in lymphoid cells) compared to currently available CD81 mAbs.
  • Excellent Western reagent and immunohistochemical reagent

Publications


  • JI, 1993 151:4090-4097 Schick and Levy: describes screen in which hybridoma was identified.
  • Leukocyte Lymphoma, 1994 1:61-64 Engel & Tedder. antibody described with other anti-CD81 mabs.

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Date Released

 6/30/2015
 

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Licensing Contact


Brenda Martino, Biological Materials Specialist
(650) 725-9119 (Direct)
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Related Keywords


screening   screening: screen   cancer   therapeutic   research tool   
 

   

  

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78-017 Monoclonal Antibodies: 11-6 anti-Ig-5b, 11-5 anti-I-A (2), 11-4 anti-H-2Kk, 11-3 anti-I-A917), 10-4 anti-Ig-5a, H-12 anti-THY 1.2
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S98-059 1D6 mab reacting with human CD81