Methods to promote bone healing in patients with diabetes

Researchers at Stanford have developed methods to enhance bone healing in diabetic patients, who often suffer from impaired fracture healing due to a deficiency in hedgehog signaling in their skeletal stem cells. By administering a hedgehog agent at the injury site, they can reverse these deficiencies and promote bone regeneration, addressing a significant medical issue for diabetic patients worldwide.

Stage of research
Using diabetic mouse models, the inventors have shown that administering a hedgehog agent to the fracture rescued bone healing.