Non-Invasive Imaging for the Detection of Human Embryonic Aneuploidy at the Blastocyst Stage

Stanford researchers have developed a non-invasive method of assessing chromosomal composition in human embryos at the blastocyst stage, thus potentially improving chances of success following in vitro fertilization (IVF). Experiments suggest that euploid human blastocysts exhibit cell cycle parameter timing that is different from aneuploid blastocysts and serve as the first example of the use of non-invasive imaging to predict ploidy at the blastocyst stage.
Given the high rate of human embryonic aneuploidy, this technology could improve IVF outcomes by reducing the transfer of aneuploid embryos, thus reducing the risk of high-order multiple pregnancies.

Figure

Stage of Research