PirB Knockout Mice (Jackson Labs MMRRC Stock Number: 030668-UCD)

PirB (PIR-B) knockout mice are genetically modified mice in which the gene encoding the PirB receptor (paired immunoglobulin-like receptor B) has been disrupted or "knocked out." PirB is a member of the immunoglobulin superfamily and plays a role in regulating immune responses, particularly in the central nervous system (CNS)