Docket #: S04-235
Scintillation Crystal Detection Arrays for Radiation Imaging Devices
A Stanford researcher has developed two advanced approaches for the positron sensitive high-energy photon sensor technology for Positron Emission Tomography (PET). In the first approach, the radiation imaging device comprises layers of very thin position sensitive scintillation detectors that provide high scintillation light collection efficiency independent of interaction location, directly measured the interaction depth of the photons within thick detection volume, and 3D positional, energy, and temporal information for each interaction in multi-interaction photon events. The benefit of this improved device is that it simultaneously facilitates high spatial resolution, high 511 keV photon absorption efficiency, high scintillation light collection efficiency, and accurate photon interaction depth measurement without compromising performance parameters important for PET.
Applications
- Nuclear Medicine--PET, SPECT
- Molecular Imaging
- Photo Imaging
- Spectroscopy
- Astrophysics
- Security Screening
- Radiation Detection/Imaging
- Homeland Defense
- Mineral Exploration
Advantages
- Uniform and ultra-high spatial resolution
- Enhance high photon detection efficiency
- High signal-to-noise ratio
- Excellent energy resolution for high image contrast and quantitative accuracy of image data
- Compatible with other imaging modalities for multi-modality platforms
Publications
- Levin CS (2002) "Design of a High-Resolution and High Sensitivity Scintillation Crystal Array with Nearly Perfect Light Collection". IEEE Transactions on Nuclear Science, 49, pp. 2236-43.
- Foudray AMK, Habte F, Levin CS, Olcott PD (2006) "Positioning Annihilation Photon Interactions in a Thin LSO Crystal Sheet with a Position-Sensitive Avalanche Photodiodes". IEEE Transactions on Nuclear Science, 53, pp. 2549-2556.
- Levin CS, Habte F, Foudray AMK, Chang J, Chinn G (2006) "Impact of High Energy Resolution Detectors on the Performance of a PET System Dedicated to Breast Cancer Imaging". Physica Medica, 21, pp. 28-34.
- Zhang J, Olcott PD, Levin CS (2007) "A New Positioning Algorithm for Position-Sensitive Avalanche Photodiodes". IEEE Transactions on Nuclear Science, 54, pp. 433-437.
- Zhang J, Foudray AMK, Olcott PD, Levin CS (2007) "Performance Characterization of a Novel Thin Position-Sensitive Avalanche Photodiode for High Resolution Positron Emission Tomography". IEEE Transactions on Nuclear Science, 54, pp. 415-421.
- Habte F, Foudray AMK, Olcott PD, Levin CS (2007) "Effects of System Geometry and Other Physical Factors on Photon Sensitivity of High Resolution Positron Emission Tomography". Physics in Medicine and Biology, 52 pp. 3753-3772.
- Levin CS (2008) "New Imaging Technologies to Enhance the Molecular Sensitivity of Positron Emission Tomography". Proceedings of the IEEE, 96, pp. 439-67.
- Pratx G, Levin CS (2009) "Bayesian reconstruction of photon interaction sequences for high-resolution PET detectors". Physics in Medicine and Biology, 54, pp. 5073-5094.
- Peng H, Levin CS (2010) "Design study of a high-resolution breast-dedicated PET system built from cadmium zinc telluride detectors". Physics in Medicine and Biology, 55, pp. 2761-2788.
Related Links
Patents
- Published Application: 20040124360
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