Researchers at Stanford University have developed a method which integrates cell barcoding and high-throughput sequencing to quantify tumor growth in genetically engineered mouse models of human cancer (called 'Tuba-seq” for Tumor barcoding coupled with seq
Researchers in Prof. Monte Winslow's laboratory have developed two viable, fertile transgenic mouse strains that enable rapid, simple generation of loss-of-function models with CRISPR/Cas9 mediated genome editing in vivo or ex vivo.