Stem cells are generally influenced by a microenvironmental niche, typically comprised of epithelial and mesenchymal cells and extracellular substrates. Many attempts have been made to produce culture systems that mimic normal intestinal epithelial growth and differentiation.
Patients with celiac disease have a pathological reaction to gluten and have either HLA-DQ2+ (90%) or HLA-DQ8+, but expression of these MHC class II haplotypes is not sufficient and other factors are necessary for the development of celiac sprue.
Inventors at Stanford University have developed a light-based 3D printing system that achieves high printing resolutions and fast printing speeds with cell-compatible natural protein biomaterials when compared to existing methods.
Researchers at Stanford University have formulated a novel biomaterial suitable for three-dimensional (3D) bioprinting: a homogeneous composite of polycaprolactone (PCL), gelatin, and beta-tricalcium phosphate.
Stanford Medicine researchers in the Mark Skylar-Scott Lab have developed "STIR" (Syringe Tumbler for Ink Resuspension), an in-syringe bioink cell mixing system with near-zero dead volume that virtually eliminates cell settling without impacting the usable amount of bio
Cell culture is a central technique used for a plethora of research applications including in the modeling of complex diseases, creating transgenic animals, gene therapy, cell therapy, regenerating lost tissue, and organ biogenesis.
Researchers at Stanford have invented a novel hydrogel with enhanced retention and extended durability. This hydrogel can be held together three times longer than many alternatives without sacrificing its self-healing attributes during injection.
Stanford researchers have designed a new 3-dimensional (3D) hydrogel cell culture system that models native tissue environment with precise control over gelation and degradation properties.
Stanford researchers developed a new technology that prints networks with distinct branch structures that emulate the natural branching observed in in vivo vascular networks.
The Heilshorn group has developed a platform for 3D bioprinting which stiffens the structure post-printing using chemistry that is completely bioorthogonal.
Current injectable hydrogel materials have fast erosion and limited tunability of their mechanical properties at different stages of applications, limiting their biomedical applications.
Engineers in Prof. Zhenan Bao's lab have developed highly conductive, stretchable composite hydrogel materials that can be used as soft electrodes that match the mechanical properties of a range of biological tissues.