Stanford researchers developed a first-in-class small-molecule inhibitor of the CLC-2 ion channel for research and drug development. CLC-2 is part of the CLC family of chloride ion channels, which regulate the flux of chloride ions across cell membranes.
Stanford researchers have developed mutant Renilla luciferase proteins and reporter gene constructs which modify the physical characteristics of the Renilla luciferase protein for use in biological assays.
Stanford researchers have engineered an exceptionally bright, cyan-excitable orange-red fluorescent protein (CyOFP) that can be used both for multiplex imaging with GFP and for high-sensitivity, bioluminescent in vivo imaging.
Stanford researchers have developed a lanthanide-doped upconverting nanoparticle (UCNP) that emits very photostable and non-blinking light, and is bright enough to delineate tumor boundaries to the naked eye during surgery.
A team of researchers at Stanford and the University of Connecticut have developed a method to deliver contrast agents through a patient-friendly sublingual or buccal film that provides prolonged continuous release for ongoing optical imaging.
Researchers in Prof. Lei Xing's laboratory have developed a radioluminescent platform to combine molecular and X-ray imaging using standard X-ray equipment coupled with a photodetector.
Researchers at Stanford have developed new fluorescent sensors to detect and monitor gastrointestinal (GI) permeability. GI permeability can be correlated with the prognosis of GI disease, thus earlier detection may lead to better patient outcomes.
Stanford researchers at the Rao Lab have developed apoptosis imaging probes with an improved new molecular structure enabling high sensitivity and stability with better performance in vivo.
Transgenic mice carrying reporter genes are extremely useful tools in modern biomedical science to unravel various underlying molecular mechanisms crucial for normal development, as well as, disease progression.
Researchers at Stanford have developed a ferumoxytol-based dual-modality imaging probe that allows for long-term stem cell tracking through MRI and early diagnosis of cell apoptosis through simultaneous fluorescence imaging.
Stanford researchers have developed a simple and effective method to sort semiconducting from metallic single walled carbon nanotubes (SWNT). This scalable technique uses semiconducting polymers to wrap around individual semiconducting SWNTs dispersed in a solution.
Stanford researchers successfully purified highly enriched semiconducting single-walled carbon nanotubes (SWNT) free of any dispersing agent via an easy, fast and scalable method.