Stanford inventors have developed a near infrared (NIR) tumor imaging platform that couples a novel rare earth cancer targeting agent and a handheld NIR-IIb fluorescence imager to enable tumor resection down to the few-cell level.
Researchers at Stanford have developed a probe, NIRDye812, which improves contrast between healthy and diseased tissues for fluorescence-guided cancer surgery applications.
Stanford researchers have developed mutant Renilla luciferase proteins and reporter gene constructs which modify the physical characteristics of the Renilla luciferase protein for use in biological assays.
Stanford researchers have engineered an exceptionally bright, cyan-excitable orange-red fluorescent protein (CyOFP) that can be used both for multiplex imaging with GFP and for high-sensitivity, bioluminescent in vivo imaging.
Stanford researchers in the Dai Lab have developed the first ultra-bright cubic-phase erbium-based rare-earth nanoparticles (α-ErNPs) with down-shifting luminescence at ~ 1600 nm for in vivo NIR-IIb (1500-1700 nm) imaging with deep penetration and high clarity.
Stanford researchers have developed a lanthanide-doped upconverting nanoparticle (UCNP) that emits very photostable and non-blinking light, and is bright enough to delineate tumor boundaries to the naked eye during surgery.
A team of researchers at Stanford and the University of Connecticut have developed a method to deliver contrast agents through a patient-friendly sublingual or buccal film that provides prolonged continuous release for ongoing optical imaging.
Researchers in Dr. Jianghong Rao's lab have developed nanoprobes for monitoring drug-induced hepatotoxicity in vivo in real time. Drug toxicity is a long-standing concern of modern medicine.
Researchers in Prof. Lei Xing's laboratory have developed a radioluminescent platform to combine molecular and X-ray imaging using standard X-ray equipment coupled with a photodetector.
Stanford researchers at the Rao Lab have developed apoptosis imaging probes with an improved new molecular structure enabling high sensitivity and stability with better performance in vivo.
Researchers at Stanford have developed a ferumoxytol-based dual-modality imaging probe that allows for long-term stem cell tracking through MRI and early diagnosis of cell apoptosis through simultaneous fluorescence imaging.
A team of Stanford engineers have developed a fast adaptive optics system for scanning, 3D imaging and sensing with a small (50 µm) multimode fiber (MMF).
Researchers in Dr. Michael Lin's lab have developed a fluorescent voltage sensor for non-invasive optical monitoring of electrical events in living cells in vitro and in vivo.