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Additional εPKC Activator Peptides to Provide Cardioprotection


Stanford Reference:

06-342


Abstract


Dr. Daria Mochly-Rosen and colleagues have identified additional εPKC activator peptides that can provide cardioprotection from ischemic damage. Also included are εPKC inhibitor peptides.

Stage of Research
In an ex vivo model of ischemia and reperfusion, the εPKC activator peptides were cardioprotective.


Applications


  • Cardioprotection from damage caused by ischemia:
    • Heart transplant

Advantages


  • Peptides are selective for εPKC

Publications



Related Web Links



Innovators & Portfolio



Patent Status



Date Released

 8/26/2013
 

Licensing Contact


Sara Nakashima, Licensing Associate
650 725 9115 (Direct)
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[-] Map/Timeline

93-168 Peptides That Modulate Interaction Between PKC and RACK
96-103 εPKC Agonists to Provide Cardioprotection
97-059 Development of a Regulatable Retroviral-Vector System for Identification of Untranslated Regions of mRNAs

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Related Keywords


ischemia   protein kinase inhibitors   protein kinase   ischemic damage   PKC   transplantation   cardioprotection   cardiovascular   epsilon protein kinase C   ischemic   protein kinase c   therapeutic: peptides   
 

   

  

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93-168 Peptides That Modulate Interaction Between PKC and RACK
96-103 εPKC Agonists to Provide Cardioprotection
97-059 Development of a Regulatable Retroviral-Vector System for Identification of Untranslated Regions of mRNAs

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