Docket #: S55-609C
129-Gt(ROSA)26Sor tml(CAG-EGFP) - Jackson Laboratory Stock Number 006053
MADM-GG mice are viable with no gross behavioral or observable abnormalities. Regardless of Cre-recombination, these mice express EGFP as their N- and C-terminal coding sequences are interrupted by the beta-actin intron in-frame high EGFP expression in every cell can be visualized in vivo and in fixed samples. These mutant mice are a control EGFP-expressing strain for use with MADM (mosaic analysis with double markers) mice. Using the MADM system, a researcher can generate genetic mosaics in which an individual organism contains somatic cells of different genotypes. This allows the researcher to ascertain lineal relationships and gene function in multicellular organisms.
Applications
- Cell differentiation and mitosis
Availability:
These mice are available directly from The Jackson Laboratory Stock Number 006053 to academic and non-profit researchers. For-profit companies must obtain a license from Stanford prior to the transfer of the mice from The Jackson Laboratory.
Similar Technologies
-
Controlling AAV receptor expression to improve testing and validation of AAV gene therapy products S15-240Controlling AAV receptor expression to improve testing and validation of AAV gene therapy products
-
Alpha 2c Adrenergic Receptor Gene Disruption Mouse (A2cARGDM) S97-238Alpha 2c Adrenergic Receptor Gene Disruption Mouse (A2cARGDM)
-
Mouse Model for Visualizing Synapses S10-195Mouse Model for Visualizing Synapses