Development of theragnostic radiopharmaceuticals for pancreatic cancer

Stanford researchers at the Ferrara Lab have developed a method to select receptor targets for molecular imaging and therapies by applying spatial transcriptomics, proteomics, and machine learning. This method has been used to identify Claudin-4 as a target for pancreatic ductal adenocarcinoma (PDAC), as well as peptides to this target to demonstrate molecular imaging. This approach can also be applied to the design of molecular imaging strategies to develop radiotheragnostics across a range of disease targets.

Stage of Development