Fluorescent Cell Barcoding (FCB) in Flow Cytometry to Enable High-Throughput Drug Screening and Large-Scale Signaling Profiling

Applications

• High-throughput screening in drug development
• Large-scale signaling profiling

Advantages

• Increased throughput, compared to current methods in flow cytometry, with an acquisition time of 5-15 minutes per 96-well plate
• Decreased cost in sample labeling with 100-fold reduced antibody consumption

Publications

• Krutzik PO and Nolan GP, "Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling." Nature Methods 3, 361 - 368 (2006)

Patents

• Published Application: 20080241820
• Published Application: 20110263457
• Issued: 8,003,312 (USA)