Docket #: S19-469
High-quality-factor metasurface for phase contrast imaging and spatial frequency filtering
Researchers at Stanford have developed an ultracompact, high-quality-factor (high-Q) metasurface that enables more convenient phase contrast imaging. Phase contrast imaging is a critical technique in biology and medicine to image essentially transparent objects such as cells. The technique is also gaining importance in the nanotechnology field. Conventionally, optical phase contrast imaging requires a set of components (annuli) placed in the Fourier plane of the imaging system. This increases the price of the imaging system and also requires tedious manual alignment. Overcoming these difficulties, the new high-Q metasurface can be used in any bright field microscope to achieve high-performance phase contrast imaging and more complex spatial frequency filtering. The optical system requires fewer, simpler parts and should be lower cost. It should also simplify alignment procedures.
Applications
- Live cell microscopy
- Nanofabricated sample examination
- In vivo retina imaging in ophthalmology
Advantages
- Greatly simplifies the microscopy system by eliminating the need to place filters in Fourier planes
- May significantly reduce the cost of phase contrast imaging
- Can lead to tunable contrast simply by changing the illumination wavelength or collection path polarizer (helpful when examining samples that have different phase profiles)
- Sizable market
Related Links
Patents
- Published Application: 20220390656
Similar Technologies
-
Light sheet fluorescence microscopy using high speed structured and pivoting illumination S16-332Light sheet fluorescence microscopy using high speed structured and pivoting illumination
-
Serpentine Optical Phased Array with Dispersion Matched Waveguides S20-131Serpentine Optical Phased Array with Dispersion Matched Waveguides
-
Drive Systems and Optimization Techniques for Photonic Bandgap (PBG) Crystals S11-504Drive Systems and Optimization Techniques for Photonic Bandgap (PBG) Crystals