MECA-32

MECA-32

A rat IgG2A MAb that recognizes an endothelial cell-specific differentiation antigen expressed by most endothelial cells in the adult, except within the central nervous system and on capillaries in skeletal and cardiac muscle. The antigen is downregulated on endothelium in association with development of the blood-brain barrier during ontogeny.

Biochemical and developmental characterization is published in Hallmann et al, Dev. Dynamics, in press.