Skin-Associated Lymphocytes and Markers (HECA-452)

HECA-452: ATCC Number HB-11485:
Rat IgM antibody to the human lymphocyte homing receptor CLA, the cutaneous lymphocyte antigen. HECA-452 defines skin-homing memory T cells, binding to the T cell carbohydrate lignad for vascular E-selectin. HECA-452 also recognizes sialyl Lewisx and sialyl Lewisa and other carbohydrate ligands for E-selectin in man. HECA-452 also recognizes E-selectin-binding epitopes of high endothelial venules in man.