Therapeutic interventions for pregnancy and related non-pregnancy conditions

Researchers at Stanford University have identified molecular regulators that can act as part of a personalized treatment plan to help treat hormone-related conditions, including pregnancy and infertility.

Hormonal and non-hormonal treatments have a broad application in pregnancy and other medical conditions. The most widely used hormonal regulators are progesterone and derived progestins, which are used to treat conditions ranging from infertility to pre-term labor. However, there is a need for more targeted and effective molecular regulators. To address this need, the Snyder lab has identified a wide array of molecular regulators using computational analysis. These regulators are both steroids and non-steroids and can be used for a variety of conditions such as recurrent pre-term delivery, amenorrhea, abnormal uterine bleeding, and hormonally sensitive cancer. The ability to provide a more specific treatment plan could potentially increase the efficacy with which these disorders are managed.