The transgenic biotracker mouse lines carry two or more broadly used reporters, and thus serve as sources for both labeled cells and tissues for transplantation and adoptive transfer experiments.
Stanford scientists in Dr. Liqun Luo's laboratory have developed a patented method for site-directed somatic cell recombination and concurrent labeling of "knock in" cells.
Researchers in the laboratory of Michael Cleary at Stanford University have developed a mouse that lacks the transcription factor Pbx1. Pbx1 is a proto-oncogene that was originally discovered at the site of chromosomal translocations in pediatric acute leukemia.
EDL (gene nomenclature, LIPG; protein, EL), gene targeted, mouse bred to homozygosity for the purposes of biological studying of EDL and the role it plays in lipoprotein metabolism.
The fosGFP Mouse was created to address a fundamental question in neuroscience and physiology: following a behavioral task or exposure to a drug, what are the changes in physiological properties of activated neurons and cells?
This mouse model of phosphodiesterase deficiency was developed using homologous recombination to knock-out the gene for PDE4D. The mice have a null PDE4D gene on C57BL/6 x 129/OLA background. These mice have proven useful in studies of asthma (see publications).
This mouse model of phosphodiesterase deficiency was developed using homologous recombination to knock-out the gene for PDE4B. The mice have a null PDE4B gene on C57BL/6 x 129/OLA background.
Myers, et al previously discovered that specific loss-of-function mutations in the human cystatin B gene on chromosome 21 cause the human genetic disease Progressive Myoclonus Epilepsy (EPM1).
Adrenergic receptors are plasma membrane proteins that mediate cellular responses to the hormone/neurotransmitters adrenaline and nonadrenaline which are released from sympathetic nerve terminals or the adrenal gland.
Adrenergic receptors are plasma membrane proteins that mediate cellular responses to the hormone/neurotransmitters adrenaline and nonadrenaline which are released from sympathetic nerve terminals or the adrenal gland.
Adrenergic receptors are plasma membrane proteins that mediate cellular responses to the hormone/neurotransmitters adrenaline and nonadrenaline which are released from sympathetic nerve terminals or the adrenal gland.