S22-038 Rejuvenating the Immune System through Depletion of Myeloid-Biased Hematopoietic Stem Cells There are two subsets of Hematopoietic stem cells (HSC); one subset that provides balanced production of myeloid and lymphoid cells, and another that is biased toward production of the myeloid lineage. Jason Ross Lara Myers Joseph Noh Kim Hasenkrug Irving Weissman