Temporally precise, noninvasive control of neural circuitry is a long-sought goal of neuroscientists and biomedical engineers. Stanford University researchers in the laboratory of Dr.
The inventors have identified and developed an archaeal light-driven chloride pump (NpHR) from Natronomonas pharaonis for temporally precise optical inhibition of neural activity. NpHR allows either knockout of single action potentials, or sustained blockade of spiking.
Ion channel dysfunctions lead to a wide array of illnesses including epilepsy, cardiac arrhythmia and type II diabetes. However, the number of clinically approved drugs for restoring normal ion channel function is limited.
Researchers in Dr. Karl Deisseroth's laboratory have developed a novel method to rapidly identify neurophysiological measures associated with psychiatric disease and then use those correlates to screen for therapeutics.
Researchers from Prof. Karl Deisseroth's laboratory have developed techniques for specifically modulating the activity of excitable cells in vivo. This approach introduces light-responsive proteins to create photo-sensitive cells.
Researchers in Prof. Karl Deisseroth's laboratory have developed a novel system for modulating brain activity with moderate intensity focused ultrasound. In this technique, ultrasound is used to increase the intrinsic firing rate of targeted neurons.
Researchers in Prof. Karl Diesseroth's laboratory have discovered a Dopamine receptor type 2 specific promoter (D2SP) that can be used to transfect, identify and isolate Dopamine R2 (D2R)-expressing cells.
The Dionne lab has developed ultrathin and compact devices for electrically driven beamsteering that fit on a semiconductor chip. These devices rely on resonant dielectric nanostructured surfaces known as "high quality factor" (high-Q) metasurfaces.
Stanford researchers at the Taylor Lab have developed software subroutines that can be used together with the open source software system Simvascular to improve the simulation of blood flow in modeling coronary arteries.
Developed at the Taylor Lab, Simvascular is an open source software package encompassing an entire cardiovascular modeling and simulation pipeline from image segmentation, three-dimensional (3D) solid modeling, and mesh generation, to
Stanford researchers have developed a simple optical device for low-power, active light tuning. The device tunes the color of light across the visible spectrum and at select wavelengths by electrical biasing an array of micron sized pixels or nanowires.
Stanford researchers have developed an efficient, virtual keyboard to facilitate independence and faster communication for those who use assistive technology.