Researchers at Stanford have discovered a powerful new optogenetic actuator- a novel red-shifted opsin. Optogenetics is a technique used to study function and communication between cells.
Stanford researchers have developed a wirelessly powered, fully internal implant which allows for optogenetic control of neurons throughout the nervous system in mammals, and in particular, mice.
Dr. Karl Deisseroth and Dr. Raju Tomer have developed a CLARITY optimized light-sheet microscope (COLM) for rapid, high-resolution imaging of large intact tissue samples.
Researchers in Prof. Karl Deisseroth's laboratory have developed a highly precise, scalable optical system for imaging or controlling thousands of individual neurons in the 3D volume accessible with a single multiphoton fluorescent microscope objective.
Researchers in Prof. Karl Deisseroth's laboratory have engineered a cytosolic, red genetically encoded calcium indicator (GECI) with high signal change at single cell resolution.
Professor Marc Levoy and collaborators have enhanced the performance of the light field microscope (LFM) by solving the problem of non-uniform spatial resolution across the working range, especially the low spatial resolution at the native objective plane (in the middle of the
Researchers in Prof. Karl Deisseroth's laboratory have developed an optical imaging and optogenetics two photon laser system that uses a single beam to illuminate many sites in three-dimensions.
Stage of research
Researchers designed electro-optical gratings for fluorescence microscopy - a drop in to existing systems with no new lenses. Researchers demonstrate a 9x improvement on FOV using Olympus 10x/0.6NA WI immersion objective at 3.3 Hz.
Researchers in Prof. Karl Deisseroth's laboratory have engineered versatile, virus-based constructs that are driven by neuronal activity to either label or optogenetically control those active neurons.
Researchers in Dr. Karl Deisseroth's lab have developed a microscope and methods to allow simultaneous recording of multiple different brain regions in a freely moving and behaving animal. There is much interest in understanding how the brain works.