Mice heterozygous for the targeted allele are viable and fertile. This polyubiquitin B (Ubb) mutation is characterized by a GFP-puror fusion protein "knock-in" allele that also abolishes endogenous gene function.
Peptidase carboxypeptidase A3 (Cpa3; originally named mast cell carboxypeptidase A14) is highly expressed in mast cells, but is also expressed in basophils and can be expressed in some populations of T-cell progenitors and thymic T cells and in certain hematopoietic progenitor
Stanford scientists in Prof. Steven Boxer's lab have invented a quantum cascade laser (QCL)-based IR spectrometer and assay for the sensitive detection of drug-protein interactions in live cells.
Researchers at Stanford University have developed an innovative hardware-based reconfigurable joint limit mechanism and module that precisely constrains a robot's workspace through pre-performance adjustments.
Stanford scientists have developed an innovative 3D brain organoid culture system derived from adult neural stem cells to model neurodegenerative diseases like Alzheimer's and enable high-throughput drug screening.
Stanford scientists have developed a gene editing approach that can correct hundreds of hotspot mutations in the COL7A1 gene locus by adapting the Easi-CRISPR strategy with only one set of single guide RNAs (sgRNA).
Stanford scientists have developed a wearable neurostimulator device that targets the dorsal genital nerve on the penis to improve and/or expedite male orgasm.
Stanford scientists have developed a strategy that enables simultaneous and combinatorial genetic screening across different types of genetic perturbations (gene knockouts, knock-ins, overexpression, and gene domain modification).