S16-189 5A6, a monoclonal antibody targeting the human tetraspanin CD81 Cancers including breast, lung, colon and prostate account for almost ten million deaths worldwide every year. The main cause of cancer deaths is metastasis, which is the propensity of cancer cells to spread throughout the body. Shoshana Levy Ranjani Rajapaksa Aurelien Marabelle Felipe Vences-Catalan Ronald Levy Chiung-Chi Kuo