Researchers in Dr. Karl Deisseroth's lab have engineered a channelrhodopsin variant that can be stimulated by red light and has fast stimulation frequencies. In neurons, channelrhodopsins are light activated protein channels that induce action potential firing.
Circulating levels of Neuromedin U (NMU) peptide are correlated with insulin resistance and obesity and dynamically regulated to suppress insulin secretion.
Researchers in Prof. Gerald Crabtree's laboratory have produced a mouse allowing high-throughput screening for activity and inhibition of virtually any chromatin modifier in any murine tissue.
Stanford researchers have developed an R-spondin1-producing cell line. The cell line is a transfectant of 293T cells expressing mouse R-spondin1 protein tagged with N-terminus HA and C-terminus Fc.
Researchers in Prof. Michelle Monje-Deisseroth's laboratory have discovered a previously unknown mechanism for glioma tumor growth and invasion that defines a novel set of therapeutic targets.
Stanford researchers have developed a cell line (MFB-F11) that can be used for an easy, sensitive, and specific bioassay to study the biological functions of Transforming Growth Factor-beta (TGF-beta).
Dr. Helen Blau and colleagues have developed a mouse model that recapitulates both the skeletal muscle and cardiac pathology seen in Duchenne Muscular Dystrophy (DMD) patients.
Dr. Rosemarie DeKruyff and colleagues have generated an agonistic TIM-1 monoclonal antibody (mAb), called TIM-1 mAb 3B3. TIM-1 plays critical roles in regulating immune cell activity and is also involved in allergic response and asthma.
Researchers in Dr. Dean Felsher's lab have generated a murine hepatocellular carcinoma (HCC) cell line with controllable MYC expression. HCC is one of the most common and incurable malignancies.
Dr. Greg Barsh and Dr. Allison Xu have generated transgenic mice that express Cre recombinase under control of regulatory elements from agouti-related protein (Agrp). The Agrp neurons are critical for regulation of a wide variety of metabolic functions.
Stanford researchers have developed a system for precise genetic modification of human embryonic stem cells (ECSs) and induced pluripotent stem cells (iPSCs).
Stanford Researchers have patented an improved technique for capturing and processing dynamic and high speed scenes using a collection of precisely timed video cameras. This system uses multiple synchronized image sensors with precise time delays to capture high-speed video.
Researchers in the laboratory of Dr. Michael Cleary at Stanford University have developed anti-Pbx1a monoclonal antibodies to study transcriptional regulation, embryonic development, and tissue homeostasis.