The lack of effective treatments for myocardial ischemia and reperfusion injury has been a major challenge in decreasing mortality rates from myocardial infarctions. Stromal cell-derived factor-1?
Patients who experience heart attacks often have immediate ischemia and cell death, which causes a decrease in cardiac function, contributing to higher mortality and morbidity.
Researchers at Stanford University have developed a novel method for the first time to generate cardiac pericytes from human induced pluripotent stem cells that closely resemble primary cells.
Stanford inventors have identified a treatment regimen that allows expansion of cardiomyocytes (CMs) derived from human induced pluripotent stem cells in vitro.
Stanford researchers have patented a photosynthetic system using a cyanobacterium solution that can be delivered to ischemic tissues, where blood flow is insufficient. This addresses a major clinical problem for patients with heart and vascular diseases.