Researchers in the laboratories of Dr. Karl Deisseroth and Dr. Peter Hegemann have engineered mutant ChR2 (Channelrhodopsin-2) proteins with light-sensitivity that is increased by orders of magnitude compared to wild-type ChR2.
Researchers in Prof. Karl Deisseroth's laboratory have engineered a novel channelrhodopsin with enhanced expression, faster speed, and improved targeting.
Researchers in Prof. Karl Deisseroth's laboratory have used optogenetic tools to develop an animal model for social dysfunction by precisely targeting defined neural circuit elements.