Stanford researchers have developed novel AsCas12a-expressing mouse models for simultaneous editing of multiple genomic loci in vivo with unique targeting capabilities relative to traditional Cas9 models, enabling the rapid creation of complex genotypes in somatic cells and ca
Researchers at Stanford University have developed a method which integrates cell barcoding and high-throughput sequencing to quantify tumor growth in genetically engineered mouse models of human cancer (called 'Tuba-seq” for Tumor barcoding coupled with seq
Researchers in Prof. Monte Winslow's laboratory have developed two viable, fertile transgenic mouse strains that enable rapid, simple generation of loss-of-function models with CRISPR/Cas9 mediated genome editing in vivo or ex vivo.