S23-552 Treating Cardiac Dysfunction with 15-PGDH Inhibition Stanford researchers have found that inhibiting 15-prostaglandin dehydrogenase (15-PGDH), which breaks down prostaglandin E2 (PGE2), can improve cardiac function in diseased and aged hearts. Helen Blau Harutiun Minas Nalbandian Geymonat Katrin Svensson