S25-419 Portable Heater-Cooler Unit for Normothermia Management in Mechanical Circulatory Support Stanford researchers have developed a highly efficient, portable heater-cooler unit (HCU) designed for normothermia management in patients on mechanical circulatory support (MCS), addressing critical limitations of current systems. Caio Carcaioli Bonin Yellappa Palagani Amit Sharir Zachary Irwin Michael Ma Alexander Reed Perry Choi