Stanford researchers developed BAP1, a strain of E. coli designed to produce complex natural products (particularly polyketides and non-ribosomal peptides) that might otherwise be inaccessible.
Researchers in Prof. Hanlee Ji's laboratory have developed an automated method to capture and directly sequence target DNA with next-generation sequencing.
Dr. Richard Zare and colleagues have developed an inexpensive, fast and simple method for treating polyethylene terephthalate (PET) blood collection tubes (BCTs) to remove bias and interference in various blood analysis procedures.
Researchers in Dr. Shoshana Levy's lab have created a pro B cell lines that provides the first B cell lineage tumors in a C57BL mouse strain. The cell lines, known as H11 and 2F3, were made by transducing mouse bone marrow with BCR-ABL retrovirus.
This invention provides a stem cell culture medium with small molecule inhibitors that can be used to maintain pluripotency in a laboratory atmospheric environment.
Researchers in Dr. Karl Deisseroth's lab have created inhibitory channelrhodopsins (ChRs) that allow fast, reversible inhibition of electrical signals in neurons. Optogenetics is a technique used to understand normal and pathological neural circuitry.
Stanford engineers have developed a patented device and sample preparation technique for high throughput purification, concentration, and sample preparation of a wide variety of biomolecules.
Dr. Brian Zabel and Prof. Eugene Butcher have developed rat monoclonal antibodies (clones BZ2E3 and BZ5B8, rIgG2aκ isotype) to the mouse chemokine (CC motif) receptor-like 2 (CCRL2) protein.
Dr. Andrea Meredith and Dr. Richard Aldrich have generated a viable mouse knockout KCNMA1, the gene encodes the pore-forming subunit of the BK large conductance calcium-activated potassium channel (also called KCa1.1, SLO1, and MaxiK).
Researchers in Dr. Michael Lin's lab have developed a fluorescent voltage sensor for non-invasive optical monitoring of electrical events in living cells in vitro and in vivo.
A team of Stanford researchers have identified a novel small molecule that could be used in vivo or ex vivo to enrich for submandibular salivary gland (SMG) stem cell (SC).
Researchers in Dr. Roeland Nusse's lab have developed a mouse monoclonal antibody to ROR2 (Nt 2535-2835). ROR2 is a membrane bound receptor tyrosine kinase that is activated by non-canonical Wnt signaling through its association with Wnt5.
Researchers in Prof. Karl Deisseroth's laboratory have developed specific, inducible animal models for depression that use targeted optogenetic strategies to precisely dissect the neuronal circuits underlying the condition.